C + Collagen™ Perfect Skin Set & Refresh Mist

An antioxidant setting mist that works triple duty to boost your skin's natural radiance.
Forallor skin types.
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Bring the dermatologist office home

This supercharged refreshing mist that hydrates and protects your skin throughout the day. With each mist, micellar technology penetrates makeup to get into your skin, delivering a doctor’s dose of antioxidants to shield you from environmental damage and revive stressed skin.

C + Collagen™ Perfect Skin Set & Refresh Mist



Our Promise

How It Works


Immediate radiance

Micellar technology penetrates into your skin delivering a doctor’s dose of antioxidants.

Long-lasting hydration

Micelles are tiny, bi-phasic droplets that carry both lipid and water soluble antioxidants.

Protect + revive

3-O Ethyl Ascorbic Acid works with collagen amino acids and a proprietary energy complex to protect and repair cellular functions.


Key Ingredients

3-O-Ethyl Ascorbic Acid is the most effective stabilized form of vitamin C - maintaining its acidic properties to penetrate deep into the skin, working on both the hydro and lipophilic phases of the cell to minimize and prevent the appearance of hyperpigmentation, fine lines, and wrinkles.

Energy Complex boosts cellular metabolism and contains antioxidant properties to protect cells and enhance functions at the nucleic level.

Micelles are tiny, bi-phasic droplets that carry both lipid and water soluble antioxidants.

See all ingredients

Our Promiseplus-sign

About Dr. Dennis Gross Dr. Dennis Gross Skincare is a dermatologist-founded brand. Dr. Gross is an unwaivering advocate for his patients, consumers, humanity, bound by the Hippocratic oath to do no harm. His mission - and ours - us to improve your skin health, how it looks, but most importantly how it makes you feel. Our #1 priority is to ensure efficacy without ever compromising safety. We are cruelty-free, paraben-free, phthalate-free, sulfate-free, and vegan. With every product we take a research backed approach and formulate with only pharmaceutical-grade active ingredients to ensure superior results, without irritation.

How It Worksplus-sign

Energy-generating formula combines vitamin C with a unique energy complex that charges skin’s battery, the mitochondria, to keep it high-functioning and toned.


1. Dual Phase Vitamin C
3-O C, a superior stabilized form of vitamin C, penetrates deep into skin targeting both oil and water phases of the skin cell.


2. Repair Skin’s Battery
Superoxide dismutase & CoQ10 protect and strengthen cell membrane to repair skin’s battery.


3. Recharge Skin’s Battery
Carnitine & niacinamide increase cellular energy to recharge skin’s battery.

How To Use

Boost your skin's natural radiance

How To Use

Boost your skin's natural radiance

Misting Spray

Hold bottle approximately 8-10 inches from face. Mist 2-3 times to treat skin and set makeup. Apply throughout the day as needed to refresh and hydrate.

The Experience

Ultra-fine refreshing mist

Complimentary Products

C + Collagen Brighten & Firm Vitamin C Serum: build collagen and brighten skin
C + Collagen Deep Cream: deep, anti-aging hydration for dry skin


C + Collagen Biocellulose Brightening Treatment Mask immediately boost skin radiance

Frequently asked questions

  • Using micellar technology, the C + Collagen Perfect Skin Set & Refresh Mist can be used before or after makeup. The actives are suspended in a special matrix for effective penetration to target areas under or on top of makeup, delivering a doctor’s dose of antioxidants to shield from environmental damage and revive tired skin.

  • 3-O C is a synthetic, bio-identical, water-soluble form of ascorbic acid with an oil-soluble ethyl chain attached to the front. This results in a biphasic, superior, more stable form of vitamin C.

  • 3-O C is biphasic, meaning it is both fat and water soluble, allowing it to penetrate to all layers of the skin cell. It has better stability without compromising bioavailability. 3-O C is an ether, not an ester, which means better absorption of ascorbic acid in skin.

Complete your routine

Free shipping on all orders + Free Samples with Every Order. some exclusions apply-