Advanced Retinol + Ferulic Intense Wrinkle Cream

An intensely hydrating wrinkle treatment powered by our Phyto-Retinol Blend™ to visibly transform skin and repair the moisture barrier for a lifted, ageless look.
Forallor skin types.
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Bring the dermatologist office home

Retinol, bakuchiol, rambutan, and ferulic acid work synergistically to help support natural collagen, visibly firm, plump, and smooth lines & wrinkles. Antioxidants arnica and centella asiatica help replenish skin's moisture barrier for a soft, hydrated, youthful complexion.

Advanced Retinol + Ferulic Intense Wrinkle Cream




Our Promise

How It Works


Diminish fine lines & wrinkles

94% of subjects immediately showed significant reduction in dry fine lines. Our unique Phyto-Retinol Blend™ combines two types of retinol with bakuchiol, rambutan, and ferulic acid to support natural collagen production and smooth fine lines & wrinkles.

Visibly lift & firm

85% of subjects saw firmer skin and improved elasticity in 2 weeks. Our unique Phyto-Retinol Blend™ combines two types of retinol with bakuchiol, rambutan, and ferulic acid to support natural collagen production for a visibly lifted, firmer appearance.

Long-lasting hydration

Clinically proven 24-hour hydration. Hyaluronic acid and glycerin deliver long-lasting hydration while arnica and centella asiatica help replenish skin's moisture barrier for a smooth, soft, hydrated complexion.

Strengthens moisture barrier

Arnica, ceramides, bakuchiol, and centella asiatica work together to help replenish skin's moisture barrier and calm skin.


In a 2-week clinical study:

94% showed a clinically significant reduction in dry fine lines
94% saw smoother skin

97% saw an improvement in overall appearance of skin
91% saw stronger and more youthful skin
85% saw firmer skin and improved elasticity


Key Ingredients

Trans-Retinol + Encapsulated Retinol smooths texture, fades dark spots, & boosts collagen.

Bakuchiol a natural alternative, provides retinol-like effects without irritation and reinforces the moisture barrier.

Ferulic Acid counteracts irritating effects of retinol and reduces sun damage.

Rambutan is an antioxidant that aids in collagen production

See all ingredients

Our Promiseplus-sign

About Dr. Dennis Gross Dr. Dennis Gross Skincare is a dermatologist-founded brand. Dr. Gross is an unwavering advocate for his patients, consumers, humanity, bound by the Hippocratic oath to do no harm. His mission - and ours - us to improve your skin health, how it looks, but most importantly how it makes you feel. Our #1 priority is to ensure efficacy without ever compromising safety. We are cruelty-free, paraben-free, phthalate-free, sulfate-free, and vegan. With every product we take a research backed approach and formulate with only pharmaceutical-grade active ingredients to ensure superior results, without irritation.

How It Worksplus-sign

1. Reinforces Moisture Barrier
Bakuchiol increases hydration and improves moisture barrier function to keep water from escaping skin.

2. Thickens Epidermis
Retinol and bakuchiol increase thickness of epidermis and dermis by increasing cell turnover in the epidermis – which stimulates collagen in the papillary dermis.

3. Strengthens Dermis
Retinol, bakuchiol, and rambutan, directly stimulate fibroblasts – collagen producing cells – in the upper dermis to produce new collagen while protecting existing collagen.

How To Use

Retinol Results, without irritation.

How To Use

Retinol Results, without irritation.


For AM/PM use. Massage into clean, dry skin including neck and décolleté.

The Experience

Rich, buttery cream

In Your Regimen

For optimal results, apply after your Dr. Dennis Gross Skincare® peel and serum. Designed for morning and night use, this retinol treatment is formulated with our Phyto-Retinol Blend™ that contains antioxidants and botanicals to soothe skin and help prevent irritation cause by UV exposure. Don’t forget to always apply a minimum of SPF 30 in the AM!

Complimentary Products

Alpha Beta® Daily Peel: transforms skin in two steps

Alpha Beta® Pore Perfecting Cleansing Gel: exfoliates and tones with AHAs and BHAs
Advanced Retinol + Ferulic Triple Correction Eye Serum: visibly lifts and firms eye areas


Experience real results with our daily moisturizers


Frequently asked questions

  • Our Phyto-Retinol Blend™ of retinol, retinol-like extracts and antioxidants work synergistically to deliver enhanced anti-aging, retexturing and complexion-clearing benefits to skin. This blend is specifically formulated to saturate skin’s natural receptors for maximum effectiveness. The percentage of retinol alone fails to capture the full breadth of the formula and its mechanism of action. Therefore, we emphasize our formula cocktail of ingredients and delivery systems over percentages for a more accurate description of product efficacy.

  • No, retinol increases thickness of both the epidermis and the dermis for overall firmer, more youthful skin. This fear refers to how traditional retinol can strip skin causing redness, flakiness and irritation. Our unique Phyto-Retinol Blend ™ reduces irritation and actually strengthens the moisture barrier while delivering enhanced complexion-clearing and collagen-building benefits to skin.

  • Our Phyto-Retinol Blend™ is specifically formulated to give enhanced benefits of retinol-use without traditional side effects such as flakiness, redness, and irritation. While some may find retinol is not suited to their skin, our Advanced Retinol + Ferulic is ideal for first-time retinol users as well as those struggling to incorporate retinol safely and effectively into their routines.

Complete your routine

Free shipping over $75 + Free Samples with Every Order. some exclusions apply-